Small intestine peroral biopsy in coeliac children.

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Small intestine peroral biopsy in coeliac children.

Since the original description of small intestine biopsy in a coeliac child by Sakula and Shiner (1957) much has been written about this method of investigation, more as it relates to adults than to children. It is our purpose to record our experience with this technique at The Hospital for Sick Children, Great Ormond Street. Although we have studied several other conditions by this method, we ...

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Ulceration of the small intestine in children with coeliac disease.

BACKGROUND Ulceration of the small intestine in children has not been previously described. PATIENTS Two children, aged 12 and 18 months, presented with a history of failure to thrive and intractable diarrhoea. RESULTS AND CONCLUSIONS Upper gastrointestinal endoscopy showed multiple ulcers involving the first and second parts of the duodenum. Histology of biopsy specimens taken from these s...

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Small intestinal biopsy in childhood coeliac disease.

Small intestinal biopsies from children with treated and untreated coeliac disease have been analysed morphometrically and compared with controls. Two methods have been used; one, described by Dunnill and Whitehead (1972) provides indices of surface-tovolume ratio and of mucosal volume. The other, described by Meinhard, Wadbrook and Risdon (1965), involves tracing the microscopic image of the b...

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Peroral small-intestinal biopsy: experience with the hydraulic multiple biopsy instrument in routine clinical practice.

Experience of the peroral, hydraulic, multiple, small-bowel biopsy instrument is recorded and compared with reported experience of other peroral biopsy instruments. It is concluded that, in routine clinical practice, there is no particular danger associated with this instrument despite warnings to the contrary. Furthermore, biopsies are obtained at least as quickly as with other instruments and...

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ژورنال

عنوان ژورنال: Gut

سال: 1966

ISSN: 0017-5749

DOI: 10.1136/gut.7.5.481